Drawing on data from the U.S. Census Bureau and Federal Bureau of Investigation, this report profiles the 2000 status and changes since 1990 in rates of: extreme poverty and concentrated poverty, adults without a high school diploma and adults with any college attendance, unemployment, and violent crime for the nation's 100 largest cities and their suburbs. The cities and suburbs are also separately examined on a unique "social deprivation" index (SDI) which integrates poverty, per capita income, no high school diploma, unemployment, violent crime, and limited English proficiency into a single measure that provides a relative ranking of community well-being. This report also highlights results of correlations conducted separately for cities and suburbs on a set of quality of life indicators with measures of racial/ ethnic diversoty and maternal/ infant health. This research shows that significant improvements were made in cities in all of the quality of life indicators that were studied, but that suburban areas generally made more progress.